[36]N.A.Peppas,E.W.Merrill,PVA hydrogels:reinforcement of radiation-crosslinked
networks by crystallization,J.Polym.Sci.Polym.Chem.Ed.14(1976)441–457.
[37]N.A.Peppas,E.W.Merrill,Differential scanning calorimetry of crystallized PVA
hydrogels,J.Appl.Polym.Sci.20(1976)1457–1465.
[38]N.A.Peppas,Hydrogels of poly(vinyl alcohol)and its copolymers,in:N.A.Peppas
(Ed.),Hydrogels in Medicine and Pharmacy,vol.2,CRC Press,Boca Raton,FL,1986, pp.1–48.
[39]S.R.Stauffer,N.A.Peppas,Poly(vinyl alcohol)hydrogels prepared by freezing–
thawing cyclic processing,Polymer33(1992)3932–3936.
[40]A.S.Hickey,N.A.Peppas,Mesh size and diffusive characteristics of semicrystalline
poly(vinyl alcohol)membranes prepared by freezing/thawing techniques, J.Membr.Sci.107(1995)229–237.
[41]N.A.Peppas,N.K.Mongia,Ultrapure poly(vinyl alcohol)hydro gels with
mucoadhesive drug delivery characteristics,Eur.J.Pharm.Biopharm.43(1997) 51–58.
[42]K.Kamath,K.Park,Biodegradable hydrogels in drug delivery,Adv.Drug Deliv.
Rev.11(1993)59–84.
[43]K.Park,W.S.W.Shalaby,H.Park,Biodegradable Hydrogels For Drug Delivery,
Technomic,Lancaster,1993.
[44]V.A.Kabanov,I.M.Papisov,Formation of complexes between complementary
synthetic polymers and oligomers in dilute solution,Vysokolmol.Soedin.A21 (1979)243–281.
[45]E.A.Bekturov,L.A.Bimendina,Interpolymer complexes,Adv.Polym.Sci.43(1981)
100–147.
[46]E.Tsuchida,K.Abe,Interactions between macromolecules in solution and
intermacromolecular complexes,Adv.Polym.Sci.45(1982)1–119.
[47]J.Klier,N.A.Peppas,Structure and swelling behavior of poly(ethylene glycol)/poly
(methacrylic acid)complexes,in:L.Brannon-Peppas,R.S.Harland(Eds.), Absorbent Polymer Technology,Elsevier,Amsterdam,1990,pp.147–169. [48]C.L.Bell,N.A.Peppas,Biomedical membranes from hydrogels and interpolymer
complexes,Adv.Polym.Sci.122(1995)125–175.
[49]T.Coviello,P.Matricardi,C.Marianecci,F.Alhaique,Polysaccharide hydrogels for
modi?ed release formulations,J.Control.Release119(2007)5–24.
[50]S.Drotleff,U.Lungwitz,M.Breunig,A.Dennis,T.Blunk,J.Tessmar,A.Göpferich,
Biomimetic polymers in pharmaceutical and biomedical sciences,Eur.J.Pharm.
Biopharm.58(2004)385–407.
[51]C.C.Lin,A.T.Metters,Hydrogels in controlled release formulations:network
design and mathematical modeling,Adv.Drug Deliv.Rev.58(2006)1379–1408.
[52]K.A.Davis,K.S.Anseth,Controlled release from crosslinked degradable networks,
Crit.Rev.Ther.Drug Carr.Syst.19(2002)385–423.
[53]N.A.Peppas,P.Bures,W.Leobandung,H.Ichikawa,Hydrogels in pharmaceutical
formulations,Eur.J.Pharm.Biopharm.50(2000)27–46.
[54]W.E.Hennink,C.F.van Nostrum,Novel crosslinking methods to design hydro gels,
Adv.Drug Deliv.Rev.54(2002)13–36.
[55]B.Amsden,Solute diffusion within hydrogels.Mechanisms and models,
Macromolecules31(1998)8382–8395.
[56]T.Canal,N.A.Peppas,Correlation between mesh size and equilibrium degree of
swelling of polymeric networks,J.Biomed.Mater.Res.23(1989)1183–1193. [57]M.N.Mason, A.T.Metters, C.N.Bowman,K.S.Anseth,Predicting controlled-
release behavior of degradable PLA-b-PEG-b-PLA hydrogels,Macromolecules34 (2001)4630–4635.
[58]G.M.Cruise, D.S.Scharp,J.A.Hubbell,Characterization of permeability and
network structure of interfacially photopolymerized poly(ethylene glycol) diacrylate hydrogels,Biomaterials19(1998)1287–1294.
[59]S.R.Lustig,N.A.Peppas,Solute diffusion in swollen membranes.9.Scaling laws
for solute diffusion in gels,J.Appl.Polym.Sci.36(1988)735–747.
[60]J.Siepmann,N.A.Peppas,Modeling of drug release from delivery systems based on
hydroxypropyl methylcellulose(HPMC),Adv.Drug Deliv.Rev.48(2001)139–157.
[61]R.Bettini,P.Colombo,G.Massimo,P.L.Catellani,T.Vitali,Swelling and drug-
release in hydrogel matrices—polymer viscosity and matrix porosity effects,Eur.
J.Pharm.Sci.2(1994)213–219.
[62]D.G.Kanjickal,S.T.Lopina,Modeling of drug release from polymeric delivery
systems—a review,Crit.Rev.Ther.Drug Carr.Syst.21(2004)345–386.
[63]A.Kikuchi,T.Okano,Pulsatile drug release control using hydrogels,Adv.Drug
Deliv.Rev.54(2002)53–77.
[64]Y.Qiu,K.Park,Environment-sensitive hydrogels for drug delivery,Adv.Drug
Deliv.Rev.53(2001)321–339.
[65]T.Miyata,T.Uragami,K.Nakamae,Biomolecule-sensitive hydrogels,Adv.Drug
Deliv.Rev.54(2002)79–98.
[66]L.E.Bromberg,E.S.Ron,Temperature-responsive gels and thermogelling polymer
matrices for protein and peptide delivery,Adv.Drug Deliv.Rev.31(1998)197–221.
[67]R.Dinarvand,A.D'Emanuele,Use of thermoresponsive hydrogels for on–off
release of molecules,J.Control.Release36(1995)221–227.
[68]T.Okano,Y.H.Bae,H.Jacobs,S.W.Kim,Thermally on–off switching polymers for
drug permeation and release,J.Control.Release11(1990)255–265.
[69]O.Hirasa,Y.Morishita,R.Onomura,H.Ichijo,A.Yamauchi,Preparation and
mechanical properties of thermo-responsive?brous hydrogels made from poly (vinyl methyl ethers,Koubunshi Ronbunshu46(11)(1989)661–665.
[70]R.Yoshida,K.Uchida,Y.Kaneko,K.Sakai,A.Kikuchi,Y.Sakurai,T.Okano,Comb-
type grafted hydrogels with rapid temperature responses,Nature374(6519) (1995)240–242.
[71]A.Kikuchi,T.Okano,Temperature-responsive polymers as on–off switches for
intelligent biointerfaces,in:T.Okano(Ed.),Biorelated Polymers and Gels, Academic Press,Boston,MA,1998,pp.1–28.
[72]A.S.Hoffman,Applications of thermally reversible polymers and hydrogels in
therapeutics and diagnostics,J.Control.Release6(1987)297–305.
[73]S.K.Vakkalanka, C.S.Brazel,N.A.Peppas,Temperature and pH sensitive
terpolymers for modulated delivery of streptokinase,J.Biomater.Sci.Polym.
Ed.8(1996)119–129.
[74]A.Serres,M.Baudys,S.W.Kim,Temperature and pH-sensitive polymers for
human calcitonin delivery,Pharm.Res.13(1996)196–201.
[75]L.C.Dong,Q.Yan,A.S.Hoffman,Controlled release of amylase from a thermal and
pH-sensitive,macroporous hydrogel,J.Control.Release19(1992)171–177. [76]C.S.Brazel,N.A.Peppas,Pulsatile local delivery of thrombolytic and antithrom-
botic agents using poly(N-isopropylacrylamide-co-methacrylic acid)hydro gels, J.Control.Release39(1996)57–64.
[77]Y.H.Bae,Stimuli-Sensitive Drug Delivery,in:K.Park(Ed.),Controlled Drug
Delivery:Challenge and Strategies,American Chemical Society,Washington,DC, 1997,pp.147–160.
[78]K.Ishihara,M.Kobayashi,I.Shinohara,Control of insulin permeation through a
polymer membrane with responsive function for glucose,Makromol.Chem., Rapid Commun.4(1983)327–331.
[79]G.Albin,T.A.Horbett,B.D.Ratner,Glucose sensitive membranes for controlled
delivery of insulin:insulin transport studies,J.Control.Release2(1985)153–164.
[80]A.A.Obaidat,K.Park,Characterization of glucose dependent gel–sol phase
transition of the polymeric glucose–concanavalin A hydrogel system,Pharm.Res.
13(7)(1996)989–995.
[81]N.Yui,T.Okano,Y.Sakurai,In?ammation responsive degradation of crosslinked
hyaluronic acid gels,J.Control.Release22(1992)105–116.
[82]N.Yui,J.Nihira,T.Okano,Y.Sakurai,Regulated release of drug microspheres from
in?ammation responsive degradable matrices of crosslinked hyaluronic acid, J.Control.Release25(1993)133–143.
[83]T.Miyata,N.Asami,T.Uragami,A reversibly antigen responsive hydrogel,Nature
399(1999)766–769.
[84]T.Miyata,N.Asami,T.Uragami,Preparation of an antigen sensitive hydrogel
using antigen–antibody bindings,Macro molecules,vol.32,1999,pp.2082–2084.
[85]B.Berner,S.M.Dinh,Electronically assisted drug delivery:an overview,in:B.Berner,
S.M.Dinh(Eds.),Electronically Controlled Drug Delivery,CRC Press,Boca Raton,FL, 1998,pp.3–7.
[86]R.Kishi,M.Hara,K.Sawahata,Y.Osada,Conversion of chemical into mechanical
energy by synthetic polymer gels(chemomechanical system),in:D.DeRossi,K.
Kajiwara,Y.Osada, A.Yamauchi(Eds.),Polymer Gels—Fundamentals and Biomedical Applications,Plenum Press,New York,1991,pp.205–220.
[87]I.C.Kwon,Y.H.Bae,T.Okano,B.Berner,S.W.Kim,Stimuli sensitive polymers for
drug delivery systems,Makromol.Chem.Macromol.Symp.33(1990)265–277.
[88]I.C.Kwon,Y.H.Bae,S.W.Kim,Electrically erodible polymer gel for controlled
release of drugs,Nature354(1991)291–293.
[89]I.C.Kwon,Y.H.Bae,T.Okano,S.W.Kim,Drug release from electric current
sensitive polymers,J.Control.Release17(1991)149–156.
[90]A.D'Emanuele,J.N.Staniforth,Feedback controlled drug delivery using an
electro-diffusion pump,J.Control.Release23(1993)97–104.
[91]E.Eljarrat Binstock,F.Raiskup,J.Frucht Pery,A.J.Domb,Hydrogel probe for
iontophoresis drug delivery to the eye,J.Biomater.Sci.Polym.Ed.15(4)(2004) 397–413.
[92]L.Brannon-Peppas,N.A.Peppas,Equilibrium swelling behavior of pH-sensitive
hydrogels,Chem.Eng.Sci.46(1991)715–722.
[93]H.A.Allcock,A.M.A.Ambrosio,Synthesis and characterization of pH-sensitive
poly(organophosphazene)hydrogels,Biomaterials17(1996)2295–2302. [94]B.A.Firestone,R.A.Siegel,Dynamic pH-dependent swelling of a hydrophobic
polyelectrolyte gel,mun.29(1988)204–208.
[95]R.A.Siegel, B.A.Firestone,pH-dependent equilibrium swelling properties of
hydrophobic polyelectrolyte copolymer gels,Macromolecules21(1988) 3254–3259.
[96]R.A.Siegel,M.Falamarzian,B.A.Firestone,B.C.Moxley,pH-controlled release
from hydrophobic/polyelectrolyte copolymer hydro gels,J.Control.Release8 (1988)179–182.
[97]A.Bilia,V.Carelli,G.Di Colo,E.Nannipieri,In vitro evaluation of a pH-sensitive
hydrogel for control of GI drug delivery from silicone-based matrices,Int.J.
Pharm.130(1996)83–92.
[98]M.G.Kodzwa,M.E.Staben,D.G.Rethwisch,Photoresponsive control of ion-exchange
in leucohydroxide containing hydrogel membranes,J.Membr.Sci.158(1999)85–92.
[99]M.Zrínyi,D.Szabó,H.G.Kilian,Kinetics of the shape change of Magnetic?eld
sensitive polymer gels,Polym.Gels Netw.6(1998)441–454.
[100]C.S.Hsu,L.H.Block,Anionic gels as vehicles for electrically modulated drug delivery.
I.Solvent and drug transport phenomena,Pharm.Res.13(1996)1865–1870. [101]S.Murdan,Electro-responsive drug delivery from hydro gels,J.Control.Release 92(1–2)(2003)1–17.
[102]von,J.Kost,Mass transport enhancement by ultrasound in nondegradable polymeric controlled release systems,J.Control.Release54(1998)1–7. [103]R.Goldbart,J.Kost,Calcium responsive bioerodible drug delivery system,Pharm.
Res.16(1999)1483–1486.
[104]A.K.Andrianov,S.Cohen,K.B.Visscher,L.G.Payne,nger,Controlled release using ionotropic polyphosphazene hydro gels,J.Control.Release27(1993)69–77. [105]Y.Suzuki,M.Tanihara,Y.Nishimura,K.Suzuki,Y.Kakimaru,Y.Shimizu,A novel wound dressing with an antibiotic delivery system stimulated by microbial infection,ASAIO J.43(1997)M854–M857.
[106]M.Tanihara,Y.Suzuki,Y.Nishimura,K.Suzuki,Y.Kakimaru,Thrombin-sensitive peptide linkers for biological signal-responsive drug release systems,Peptides19 (1998)421–425.
[107]Y.Suzuki,M.Tanihara,Y.Nishimura,K.Suzuki,Y.Kakimaru,Y.Shimizu,A new drug delivery system with controlled release of antibiotic only in the presence of infection,J.Biomed.Mater.Res.42(1998)112–116.
1646M.Hamidi et al./Advanced Drug Delivery Reviews60(2008)1638–1649