“In our manuscript, we draw the conclusion that the loss of enteric neuropathy may due to reduction of GDNF and its main downstream signaling pathway PI3K/Akt, at least partly. The conclusion was made as it might be PI3K/Akt is a survival signal for enteric neurons. However, there are still some limitations in this present study. First, p-Akt/Akt might be more effective index that should be substitute for p-Akt/neurons; …... “ 心得感悟:
1.只要有机会,就要抓住;
2.直面问题,不要顾左右而言它,能解决一点的解决一点,突出说明....其它不明说明的,呵呵,放在discussion中又何妨..