Inconclusion,itwasrevealedthathighlysolublehalfN-acetylatedchitosancouldbepreparedthroughasimpleandimprovedmethod:reductionofthemolecularweightof
274N.Kubotaetal./CarbohydrateResearch324(2000)268–274
chitosan,followedbyN-acetylationinaqueousaceticacid.ThehalfN-acetylatedchitosanthusobtainedhadarandomdistribu-tionoftheN-acetylgroups,andthelowerthemolecularweight,thehigherthewatersolubil-ity.Furthermore,thesolubilityofthehalfN-acetylatedchitosaninaqueousorganicsol-ventsalsoincreasedwithdecreasingmolecularweight.References
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