制和肿瘤细胞不易凋亡有关。另一方面 ，肿瘤组织内某些蛋白酶基因在的过度表达和调控失常在肿瘤细胞凋亡中所起功能也应值得进一步探究探索。
参考文献
1 Steller H. science, 1995;267摘要:1445-1449
2 Sarin A, adams DH, Henkart PA. J Exp, med, 1993;178摘要:1693-1700
3 Bruno S, Bino gD, Lassota P, et al. Leukemia, 1992;6摘要:1113-1120
4 Komiyama T, ray C, Pickup D, et al. J Bid. Chem, 1994;269摘要:19331-19337
5 Kuida K, lippke J, Ku G, et al. Science. 1995;267摘要:2000-2002
6 Kostura MJ. proc Natl. Acad. Sci USA, 1989;86摘要:5227-5231
7 Enari M, Hug h, Nagata S. Nature, 1995;375摘要:78-81
8 Walker NPC, talanian RV, Brady KD, et al. Cell, 1994;78摘要:343-352
9 Miura M. friedlander RM, Yuan J. Proc Natl Acad Sci USA, 1995;92摘要:8313-8322
10 Wang L, miura M, Bergeron L, et al. Cell, 1994;78摘要:739-750
11 Tcwari M, quan LT, O’Rourke K, et al. Cell, 1997;81摘要:801-809
12 Faucheu C, diu A, Chan A, et al. J, Emko 1995;14摘要:1914-1922 1
3 Boekel JC, J immund, 1995;154要:1707-1716
14 Gu Y, sarnecki C, Aldape RA, et al. J Biol. Chem, 1995;270摘要:18715-18718
摘
15 Irmler m,Herti g S, MacDonald HR. J. Exp. Med, 1995;181摘要:1917-1922
16 Smyth MJ, trapani JA. Immunol. 1995;16摘要:202-206
17 Ciechanover a. Cell, 1994;79摘要:13-21
18 LoniS PD.J. emko 1996;15摘要:3861-3870