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雷贝拉唑三联疗法治疗幽门螺杆菌阳性消化性溃疡临床疗效
作者:宁红建
来源:《中国实用医药》2016年第33期
【摘要】 目的 通过雷贝拉唑三联疗法与常规饮食治疗疗效对比, 观察雷贝拉唑三联疗法对幽门螺杆菌阳性消化性溃疡患者的临床疗效, 为疾病的治疗提供临床经验。方法 66例幽门螺杆菌阳性消化性溃疡患者, 随机分为观察组及对照组, 各33例。对照组患者给予常规饮食疗法治疗, 观察组患者给予雷贝拉唑三联疗法治疗。观察两组患者不良反应发生情况及疗效。结果 观察组总有效率为90.91%, 高于对照组的69.70%, 差异具有统计学意义(χ2=4.69, P
【关键词】 雷贝拉唑;幽门螺杆菌;消化性溃疡 DOI:10.14163/j.cnki.11-5547/r.2016.33.052
Clinical effect by rabeprazole triple therapy in the treatment of positive helicobacter pylori peptic ulcer NING Hong-jian. Department of Gastroenterology, First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China
【Abstract】 Objective To observe clinical effect by rabeprazole triple therapy in the treatment of positive helicobacter pylori peptic ulcer through curative effect comparison between rabeprazole triple therapy and conventional diet therapy, in order to provide clinical experience for disease
treatment. Methods A total of 66 patients with positive helicobacter pylori peptic ulcer were randomly divided into observation group and control group, with 33 cases in each group. The control group received conventional diet therapy, and the observation group received rabeprazole triple therapy. Observation was made on adverse reactions and curative effects in both groups. Results The
observation group had higher total effective rate as 90.91% than 69.70% in the control group, and the difference had statistical significance (χ2=4.69, P
【Key words】 Rabeprazole; Helicobacter pylori; Peptic ulcer
十二指肠或胃部的慢性溃疡在人群中发病率较高, 其症状包含消化性溃疡的主要病理特征, 在临床治疗上发生较为普遍[1-4]。十二指肠和胃溃疡的形成有多种原因, 有药物因素、饮食因素、感染因素, 其中酸性胃液功能紊乱对消化道黏膜的消化作用是常见原因[5-8]。有研究表明, 阳性消化性溃疡形成的罪魁祸首是幽门螺杆菌。本文意在通过雷贝拉唑三联疗法与常规饮食治疗疗效对比, 观察前者对幽门螺杆菌阳性消化性溃疡相关临床疗效优势。现经过治疗与随访, 发现前者疗效较为明显, 现对详细治疗过程以及心得体会总结如下。