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三黄泻心汤联合奥美拉唑治疗对抗血小板聚集药物所致上消化道出血患者疗效及血流动力学的影响
作者：杨婷
来源：《世界中医药》2017年第04期
摘要目的：探讨三黄泻心汤联合奥美拉唑治疗对抗血小板聚集药物所致上消化道出血患者疗效及血流动力学的影响。方法：选取2013年7月至2015年9月我院收治上消化道出血患者中由抗血小板药物所致的上消化道出血180例。随机分为2组：A组90例，采用三黄泻心汤联合奥美拉唑治疗；B组90例，采用垂体后叶素治疗，观察记录2组患者止血时间，对比2组患者治疗疗效，治疗前后脾静脉和门静脉血流量。结果：治疗前2组患者脾静脉和门静脉差异未见统计学意义（P>005）；治疗后，2组患者脾静脉和门静脉均有所下降，且A组患者下降的幅度大于B组，差异有统计学意义（P
关键词三黄泻心汤；上消化道出血；奥美拉唑；抗血小板药物
AbstractObjective：To study sanhuangxiexin decoction combined with omeprazole on curative effect and hemodynamics in patients with upper digestive tract hemorrhage induced by antiplatelet aggregation drugs.
Methods：Totally 180 cases of upper digestive tract hemorrhage caused by antiplatelet drugs hospitalized from July 2013 to September 2015 were randomly divided into two groups：90 cases in group A，treated with sanhuangxiexin decoction combined with omeprazole； 90 cases in group B，treated with pituitrin，observing hemostasis time and comparing curative effect between the two groups as well as blood flow rate of spleen vein and portal vein before and after the
treatment.Results：Before treatment，there was no statistical difference in two groups of patients′ spleen vein and portal vein （P>005）； after treatment，all patients′ spleen vein and portal vein decreased，group A more heavily，and the difference was statistically significant （P
Key WordsSanhuangxiexin decoction； Hemorrhage of upper digestive tract； Omeprazole； Antiplatelet drugs
中图分类号：R259；R242文献标识码：Adoi：10.3969/j.issn.1673-7202.2017.04.021 近年来随着经济的发展，人们生活水平的提高及社会老龄化等诸多因素，致使动脉粥样硬化疾病的发病率逐年上升，譬如：脑梗死、稳定性心绞痛、不稳定性心绞痛、心肌梗死和外周动脉疾病等。临床医师将抗血小板药物应用于上述疾病，以便预防心脑血管事件的发生。抗血