佩尔在神经外科的临床应用
脑保护
佩尔®:升高的颅内压可逐渐降低至正常水平佩尔®对急性脑疾病患者颅内压的影响ICP(mmHg)
20 16 12 815.56
脑外伤13例,SAH 11例,脑内出血3例,脑室 内出血1例,动静脉畸形和低氧脑损伤各1例
P<0.0512.16
11.82
40用药前 用药后4h 用药后8h
Taylon C,Roberts JM,Puri V,et al. Management of hypertensive emergencies in acute brain disease: evaluation of the treatment effects of intravenous nicardipine on cerebral oxygenation. Journal of neurosurgery.2008-12;109(6):1065-74.