治疗后停药袁一段时间后需要再度使用BLs则仍然需要再次脱敏遥
结论
正确判断BLs超敏反应需要详尽的病史袁恰当的皮肤测试和/或体外诊断袁必要时需要行药物激发试验才能明确遥一个完整科学的药物过敏问卷有利于采集到诊断必需的病史要点曰皮肤测试需要选择合适的皮试液袁要兼顾侧链抗原决定簇曰体外诊断中袁免疫分析法测定特异性IgE敏感度低但特异性高袁而嗜碱性粒细胞活化试验对于体外检测药物速发型变态反应是值得开展的检查曰淋巴细胞转化试验对于非速发型药物变态反应的检测有一定意义袁但后者的诊断可能更有赖于设计良好的药物激发试验遥对于有BLs过敏史的患者袁使用抗生素以前进行BLs皮肤试验或许有助于避免盲目的滥用二线抗生素袁必要时进行BLs脱敏也是治疗的选择遥
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